maxi-cells

maxi-cells
Макси-клетки — бактериальные клетки, у которых хромосомная ДНК деградирована в результате облучения УФ лучами. Репликация и транскрипция в таких клетках ингибированы (угнетены) из-за неспособности поврежденной ДНК быть для них шаблоном. Однако если М. содержат множественные копии плазмид, то плазмиды, которые не были подвержены УФ воздействию, продолжают реплицироваться и транскрибировать генные продукты. Т. обр., М. имеют значение для анализа функций, кодируемых плазмидами, тогда как продукты, кодируемые геномом хозяина, сведены к минимуму (ср. Мини-клетки).

Англо-русский толковый словарь генетических терминов. — М.: Изд-во ВНИРО. . 1995.

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